Glutathione 250 mg
Astaxanthin 6 mg
Niacinamide 250 mg
Collagen <500 Da
HA · 3 MW
GL-01 sachet · 15 ml liquid shot · pineapple
GL-01 · Skin longevity

Eight actives.
One daily shot.

The full 4×8 protocol in a single 15 ml liquid shot — pineapple flavored, no sugar added. Four mechanisms, eight evidence-led actives, each dosed at the level published clinical evidence showed effect. Tear, drink, done.

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Read the science first →
Format
Liquid shot
15 ml sachet · 30 ct
How to use
1 daily
AM or PM · 2 are even better
Flavor
Pineapple
no added sugar · vegan
Key grades
Setria® · AstaReal®
trial-grade actives
When you'll notice
4 → 8 → 12 wk
hydration → tone → firmness
Made in
USA
cGMP · Prop. 65 compliant
Tested
Heavy metals · micro · potency
3rd-party, every batch
What's in the canister

One canister.
30 days of glo.

30
single-dose sachets
15 ml each · individually sealed · ready to tear, anywhere
  • 30-day rolling refill, ships every month on subscription
  • Single-serve sealing prevents astaxanthin & glutathione oxidation
  • Recyclable canister, sachets sized for travel and pocket carry

What you'll notice.
And when.

Most longevity supplements ask you to wait three months on faith. We won't. There's a real, early signal — and a slower, structural change underneath. Both are measured. We'd rather you know which is which.
  1. Day 5–7
    What you'll feel first

    An early signal.

    Skin holds makeup differently. Looks brighter under indoor light. Feels smoother under your fingers. The barrier rehydrates first — and that changes how light reflects off your skin.

    The mechanismHyaluronic complex restores stratum-corneum hydration. Glutathione drops the immediate antioxidant load. Light reflectance shifts. Real, but it's the surface — not the structure.
  2. Week 4–8
    What others will notice

    A visible change.

    Tone evens out. Pigmentation drift starts to settle. The barrier holds water through the day instead of needing reapplication. People who haven't seen you in a month start asking.

    The mechanismTyrosinase regulation kicks in (glutathione, white tomato, niacinamide). TEWL drops measurably. Melanocyte activity quiets. Visible to the eye, measurable to the Corneometer.
  3. Week 12+
    What's happening underneath

    The longevity work.

    Dermal collagen density. Elasticity recovery. Cumulative oxidative defense. The part you don't see in the mirror — measured by Cutometer, 8-OHdG, collagen echo density. The part longevity science actually cares about.

    The mechanismCollagen peptide stimulates fibroblast Type I synthesis. Astaxanthin protects membrane lipid from peroxidation. Niacinamide feeds NAD⁺. Measured in months, not days.

Most ingestibles either chase the early signal (and lose all longevity credibility) or hide it (and lose all retention). We'd rather be honest about both. The early signal earns you the first week. The longevity work earns you the years.

The eight,
explained.

Eight actives, organized into four functional complexes. Each dosed to the level the clinical evidence supported — printed in milligrams on the label. Full mechanism detail →
Glutathione 250 mg
L-Cysteine 240 mg
White tomato 30 mg
Niacinamide 250 mg
HA complex 120 mg
Milk ceramide 40 mg
Collagen 1,000 mg
Astaxanthin 6 mg
01
Tone & Melanogenesis Complex
Total · 790 mg · 4 actives
N°01
Glutathione
글루타치온 · reduced (GSH)
Grade: Setria® · Kyowa Hakko, Japan
Inhibits tyrosinase via copper chelation; shifts melanin synthesis from eumelanin to pheomelanin; quenches intracellular ROS. Oral bioavailability demonstrated in RCT at this dose.1
Daily dose250 mg
N°02
L-Cysteine
L-시스테인 · GSH precursor
Grade: Pharma-grade free-form
Rate-limiting precursor in endogenous glutathione synthesis. Supplies the cysteine moiety for GSH production — the step most supplements ignore entirely.1,2
Daily dose240 mg
N°03
White tomato extract
화이트토마토 추출물 · phytoene + phytofluene
Std: ≥7% phytoene + phytofluene
Colorless carotenoids from non-pigmented Solanum lycopersicum. Absorb UV-B / UV-A1; deposit in skin with 12 wk oral dosing; reduce UV-induced pigmentation drift.3
Daily dose30 mg
N°04
Niacinamide
나이아신아마이드 · vitamin B₃
Grade: USP-grade nicotinamide
Inhibits PAR-2-mediated melanosome transfer; downregulates MMP-1; precursor to NAD⁺ via Preiss-Handler pathway for sirtuin-mediated DNA repair.4,5
Daily dose250 mg
02
Barrier & Hydration Matrix
Total · 160 mg · 2 actives
N°05
Hyaluronic complex · 3 MW
히알루론산 복합물 · HMW / MMW / LMW
Source: biofermented · non-animal · 3 MW fractions
Three molecular weights targeting three anatomical hydration layers: HMW (~1 MDa) surface, MMW (~200 kDa) intermediate, LMW (~10 kDa) mid-dermis. Reduces TEWL at 120 mg/day in 12-wk RCT.6
Daily dose120 mg
N°06
Milk ceramide
밀크 세라마이드 · Cer[NS/NP/AP]
Source: sphingomyelin-enriched milk lipid · enzyme-hydrolyzed
Restores stratum-corneum lamellar lipid lamellae. Delivers Cer[NS], Cer[NP], Cer[AP] — the ceramide subtypes the epidermis loses with age. Clinically associated with ↓ TEWL at 30–50 mg/day.7
Daily dose40 mg
03
Dermal Structure Peptide
Total · 1,000 mg · 1 active
N°07
Collagen peptide · <500 Da
초저분자 콜라겐 펩타이드
Source: Marine Type I · mean MW <500 Da · enriched Pro-Hyp / Hyp-Gly
Hydrolyzed to ultra-low MW for intact intestinal absorption. The Pro-Hyp and Hyp-Gly dipeptides are detected intact in plasma post-ingestion and directly stimulate dermal fibroblast collagen synthesis. Why 1,000 mg instead of 5–10 g: at <500 Da, peptide bioavailability per gram is dramatically higher than bulk collagen. The dose is calibrated to bioavailable dipeptide delivery — not gross intake.8
Daily dose 1,000 mg
04
Cellular Defense Antioxidant
Total · 6 mg · 1 active
N°08
Astaxanthin
아스타잔틴 · keto-carotenoid
Grade: AstaReal® natural · Haematococcus pluvialis · closed-system photobioreactor
Natural 3S,3′S stereoisomer — not synthetic. Spans the full cell membrane lipid bilayer, providing antioxidant protection from both inner and outer leaflet. Singlet-oxygen quenching capacity ~6,000× vitamin C. Reduces UV-induced MMP-1 upregulation, improves visco-elastic skin parameters at 6–8 mg/day vs. placebo in RCT. Glutathione (N°01) also operates in cellular defense and is cross-attributed to Complex 01.9
Daily dose 6 mg
Dose validation

What the studies
actually used.

No proprietary blends. Every milligram printed. Below: the studied dose from published trials, what typical OTC products deliver, and where glo sits.1–10

Active
Studied dose
Typical OTC
glo GL-01
Glutathione (reduced)
250–500 mg
50–100 mg
250 mg · Setria®
L-Cysteine
240–500 mg
often omitted
240 mg
White tomato (phytoene+PF)
~30 mg
5–15 mg
30 mg · std. ≥7%
HA complex
120–200 mg
50–100 mg (1 MW)
120 mg · 3 MW
Milk ceramide
30–50 mg
often omitted
40 mg · Cer[NS/NP]
Collagen peptide (<500 Da)
1–2.5 g (low-MW)
5–10 g (bulk)
1,000 mg · <500 Da
Astaxanthin
4–12 mg
2–4 mg (often synthetic)
6 mg · AstaReal® natural
Niacinamide
100–500 mg
25–250 mg
250 mg · USP-grade

Full dose rationale and primary references — including the collagen MW bioavailability discussion — available on the Science page.

The ritual

One shot.
Anytime.

That's the whole protocol. Tear the sachet, drink the shot, done. Skin longevity is a measured-in-months thing — built for consistency, not theater.

01
Tear, drink the 15 ml shot.
Pineapple flavored. No mixing, no water needed. Best taken with food — particularly helps absorption of astaxanthin and the carotenoid fraction — but anytime works.
Daily
02
Stack with what you already do.
Designed to sit alongside your existing topicals, retinoids, sunscreen and any other supplements. Not a replacement for SPF — never has been.
Compatible
03
Notice the windows: 4 → 8 → 12 wk.
Hydration first (week 4–6). Tone evenness next (week 8–12). Firmness changes are a 12-week window. Cellular defense is cumulative — measurable, just not in the mirror.
Built-in
04
Questions? Email SciCare.
Real questions answered by our science team. Drug interaction check, dose questions, anything else. Replies typically within one business day.
scicare@
Testing & QA

What's not in it
matters too.

Every batch tested third-party before release. COAs available to practitioners and members on request via official@weglow.biz.

01
Heavy metals
Below safe limits
Lead, arsenic, cadmium, mercury — every batch screened to U.S. Pharmacopeia oral safety limits.
02
Microbiology
Pathogen screened
No detectable E. coli, salmonella, or Staph. Total aerobic count, yeast and mold within compendial limits. Every lot.
03
Potency
HPLC verified
Every active assayed pre-release. What's on the label is in the shot, ±10%.
04
Facility
cGMP · Prop. 65
cGMP-certified manufacture, USA. Prop. 65 elemental thresholds respected.
Questions

The ones
we get most.

Full clinical reasoning on the Science page. SciCare team answers within one business day.

Why eight actives instead of one, dosed higher?+
Because skin ages along four parallel mechanisms — tone, barrier, structure, oxidative defense — and no single ingredient addresses more than one. There's no dose of glutathione that also restores ceramide. The 4×8 protocol gives each mechanism at least one dose-validated active.
Why is the collagen dose only 1,000 mg?+
Because molecular weight — not gross intake — is the rate-limiting absorption variable. The collagen in glo is hydrolyzed to <500 Da, enriched for the Pro-Hyp and Hyp-Gly dipeptides that cross the intestinal epithelium intact. Sub-500 Da peptides deliver meaningfully higher bioavailability per gram vs. bulk collagen powder. Full rationale on the Science page.
What does "trial-grade form" mean?+
Where a clinical trial used a specific identifiable form — Setria® reduced glutathione, AstaReal® natural astaxanthin — glo uses that exact form. Reduced vs. oxidized glutathione, natural vs. synthetic astaxanthin, have different in-vivo profiles. Form discipline is inseparable from dose discipline.
Is this safe with my current prescriptions?+
For most people, yes — the actives in glo are well-tolerated and have a long evidence base. But if you're on anticoagulants (e.g. warfarin), oral isotretinoin, hormonal therapy, thyroid medication, or any hepatic CYP450 substrate, please consult your physician before starting. Email official@weglow.biz with specific drug-interaction questions and our science team will reply with the relevant literature.
When will I notice something?+
Hydration: typically measurable at weeks 4–6. Tone: visually noticeable around weeks 8–12. Firmness: Cutometer changes at 12 weeks. Oxidative defense markers (↓ 8-OHdG) are cumulative — the longevity part, not the mirror part.
What's the refund policy?+
90-day full refund, including used product, if you've taken the protocol as written and aren't seeing change. We'd rather refund you than have you on something that isn't working.
Verified reviews

What members
are saying.

4.8
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Based on 12,475 verified reviews
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Amelia NYC
✓Verified Reviewer
★★★★★

My skin held water like it hadn't in years. Hydration shows up first — by week 3 I noticed it didn't matter as much if I forgot moisturizer.

04/22/26
Helpful?
Jiwoo Seoul
✓Verified Reviewer
★★★★★

Took it for the melasma after my second pregnancy. By week 8 the tone was visibly more even. My dermatologist confirmed at my follow-up.

04/15/26
Helpful?
Marcus LA
✓Verified Reviewer
★★★★☆

Pineapple flavor is mild — not sweet — easy first thing in the morning. Shot is small enough that I never skip the daily.

04/02/26
Helpful?
Rachel SF
✓Verified Reviewer
★★★★★

I've taken collagen separately for years. glo is the first thing where I felt the difference. The barrier improvement was the unexpected bonus.

03/28/26
Helpful?
Daniel Chicago
✓Verified Reviewer
★★★★☆

Real results take time. Hydration at 4 weeks. Tone at 8. Firmness around 12. I appreciated that the brand was clear about timeline rather than promising overnight.

03/14/26
Helpful?
Hye-jin Seoul
✓Verified Reviewer
★★★★★

By week 8 friends started asking what procedure I'd had. None — just one shot of glo daily. Pineapple makes it easy to remember.

02/28/26
Helpful?
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GL-01

Eight actives.
One ritual.

One pineapple shot, daily. Ships free. 90-day refund if it doesn't work.

Add to cart → Meet the 8 specialists
$79 / month on subscription · $89 one-time · Not available in all states